Ellis Developments Limited

Nottingham, United Kingdom

Home Up 

The Histological In-growth of Soft Tissue into the Nottingham Hood Prosthesis

 P Durani, I-H Jeon, TA McCulloch, A McLeod, WA Wallace

Nottingham Shoulder & Elbow Unit

Nottingham City Hospital

The Nottingham Hood

 l A polyester soft tissue reinforcement device

 l Used as reinforcement for patients with shoulder arthroplasties complicated by medium or large tears of the rotator cuff (RCTs)

 l Introduced in 1987, number of modifications made since then

 l Used on a named patient basis for 10 years on humanitarian grounds – alternative option for patients with massive RCTs

 l 30 Nottingham Hoods inserted over the past 10 years

 Aim

 l Investigate the histological changes associated with the Nottingham Hood:

• Amount of fibrous tissue ingrowth

• Level of inflammatory reaction

 l How do the histological changes vary with length of time from implantation ?

 

The Nottingham Hood

Embroidered polyester – can be cut without fraying

Anterior

Flange

Middle

Flange

Posterior

Flange

Holes for Hook attachment

Hooks on stem

 

 

 

Polyethylene

Glenoid

Humeral Stem

Posterior Flange

Sutured

 

 Method

 l 4 patients who have had shoulder prostheses with a  Hood inserted for associated massive RCTs

 l Re-operations for various reasons

 l Excised material subject to histological analysis

 l Excised biopsy material obtained at 6 weeks, 5 months, 9 months and 14 years

 l Routine and polarised light microscopy has been used in all cases

 RESULTS

Patient 1

 l 87 yr old lady with severe arthritis; bilateral TSRs – satisfactory left TSR but unstable right TSR.

 l Suffered CVA, left sided hemi-plegia – became dependent on Right shoulder for ADLs

 l Right TSR revision: glenoid component removed, glenoplasty, humeral head relocated with a Nottingham Hood to retain it in position

 l Operated shoulder re-dislocated while nursing staff moving patient in bed

 l Re-op: glenoid reconstructed, Hood removed

 

Polarised Light Microscopy:  Patient 1 (at 6 weeks)

 

 

 

 

 

 

Polyester material

Thrombus

 

Polyester material

Red blood cells

Fibrin

High Power Microscopy : Patient 1 (at 6 weeks)

 Results : Patient 2

 l 76 yr old lady with bilateral lower limb amputations after an accident at 17 years old

 l Severe arthritis of weight-bearing left shoulder : left TSR carried out

 l Several revisions: stabilised anteriorly with reinforcement from Nottingham Hood

 l Visualised at a re-operation 5 months later, and biopsy taken

 

Intra-Op Macroscopic Features (at 5 months)

 

Nottingham Hood In Situ

Anterior flange of Hood

 

Polarised Light Microscopy:  Patient 2 (at 5 months)

Polyester Material

Fibrous tissue

 

Polyester material

Fibrin

Collagen

 

High Power Microscopy : Patient 2 (at 5 months)

Results: Patient 3

 l 73 year old man with severe arthritis, a complete rotator cuff tear and anterior dislocation of Left shoulder

 l Nottingham Hood inserted with a Left Neer prosthesis in 1989

 l Revision operation 9 months later due to loose glenoid. Nottingham Hood removed at this time, and sent for histology.

 

Routine Microscopy: Patient 3 (after 9 months)

4 strands of polyester material

Fibrous tissue

High Power: fibrous tissue

ingrowth of polyester strands

Results: Patient 4

 l 66 yr old with bilateral shoulder arthritis; right shoulder hemi-arthroplasty in 1988

 l Co-existent massive RCT augmented with Nottingham Hood (early version)

 l Continued problems, Right revision hemi-arthroplasty in 2002

 l Nottingham Hood (early version) removed and analysed; replaced with Nottingham Hood (latest version)

 

Polarised Light Microscopy:  Patient 4 (after 14 years)

Polyester material

Surrounding Collagen

 

Polyester fibres

Fibrin

Fascia-like Collagen

 

High Power Microscopy: Patient 4 (at 14 years)

 

Masson-Trichome Stain : Patient 4 (after 14 years)

Polyester

Collagen

Summary of Results

 

Case No.

Age

(yrs)

Sex

Time at Biopsy

Histology

1

87

F

6 weeks

Fibrin insinuated between bundles of meshwork. Thrombus like formation. No true ingrowth

2

76

F

5 months

Granulation and fibrous tissue. FB giant cell response.

 

3

 

73

 

M

 

9 months

Strands of polyester material surrounded by new fibrous tissue ingrowth.

 

4

 

66

 

M

 

14 years

Foreign material arranged as parallel fibres within tissue. Invested with layer of fascia-like collagen. Associated FB giant cell reaction.

 Conclusion

 l Early organisational response to the insertion of  the new material

 l Long-term incorporation into host tissues by fibrosis and scarring

 l Small fibrin and foreign body response lingers on

 l Suggests long-term implantation of polyester as reinforcement of RCTs is not associated with serious biological problems

 

END

With acknowledgements to the authors:  P Durani, I-H Jeon, TA McCulloch, A McLeod, WA Wallace

Julian Ellis will be delighted to hear from you. Telephone on +44 (0) 1636  812100

email: info@ellisdev.co.uk We are based at The Stables, Hall Farm, Kirklington, Newark, Nottinghamshire, NG22 8NN,, United Kingdom